Negative contrast electron microscopy of purified virus.

Vesicular stomatitis virus, purified from an infected cell culture. This is an important pathogenic virus of cattle, causing fever and vesicles in the mouth and on the feet. Negatively stained virions: note that they are clearly "bullet shaped" just like rabies virus. Magnification approximately x40,000.

Micrograph from F. A. Murphy, University of Texas Medical Branch, Galveston, Texas.

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