BS, 1968 – Butler University, Indianapolis, IN MS, 1971 – Indiana University, Indianapolis, IN MD, 1972 – Indiana University, Indiana, IN PhD, 1976 – Indiana University, Indiana, IN
Use of cytochrome P-450 isoenzyme patterns to predict individual toxicity risk for drugs and chemicals that undergo metabolic activation.
Sedation and analgesia.
Use of anti-oxidant/NMDA antagonist therapies to decrease anoxic brain injury.
Use of urinary thioether excretion as an index of exposure to environmental chemicals.
Use of gastrointestinal dialysis to enhance removal of environmental/occupational chemicals from deep compartment body storage sites.
Application of stochastic control theory Bayesian population pharmacokinetics to improve individual patient therapeutics.
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Klein, G. and Snodgrass, W.R. (2000) Food toxins
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vol II, Kiple K.F. and Ornelas, K.C. (eds) Cambridge University Press,
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Snodgrass, W.R. (1996) Clinical
Toxicology. Casarett and Doull's Toxicology: The Basic Science of
Poisons, 5th ed, Klaassen CD, ed, McGraw-Hill, NY. 969-986.
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Lippincott Williams & Wilkins, Philadelphia PA, 2005:841—847
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Spurgeon, A., and van Gemert, M. (1999) Analysis of chlorpyrifos
exposure and human health: expert panel report. J. Toxicol Environ
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