BS, 1968 – Butler University, Indianapolis, IN MS, 1971 – Indiana University, Indianapolis, IN MD, 1972 – Indiana University, Indiana, IN PhD, 1976 – Indiana University, Indiana, IN
Use of cytochrome P-450 isoenzyme patterns to predict individual toxicity risk for drugs and chemicals that undergo metabolic activation.
Sedation and analgesia.
Use of anti-oxidant/NMDA antagonist therapies to decrease anoxic brain injury.
Use of urinary thioether excretion as an index of exposure to environmental chemicals.
Use of gastrointestinal dialysis to enhance removal of environmental/occupational chemicals from deep compartment body storage sites.
Application of stochastic control theory Bayesian population pharmacokinetics to improve individual patient therapeutics.
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