Radical Cystectomy Survival Calculator

We developed a nomogram assessing predictors for 3- and 5-year overall and cancer-specific survival derived from 5,325 patients aged 66 years of age and older derived from the Surveillance, Epidemiology, and End Results (SEER) Medicare-linked cancer registry in the United States. The nomogram was validated in the Texas Cancer Registry Medicare-linked database which predicted 3- and 5-year overall and cancer-specific survival rates with a Concordance-Indices of 0.65 and 0.66, respectively. We did not observe a significant association between radical cystectomy and non-cancer survival (HR 1.00; 95% CI, 0.81 to 1.23, p=0.999) thus limiting the effect of unmeasured confounding by indication or selection bias in the development of the nomogram. This nomogram has been converted into the Radical Cystectomy Survival Calculator© (RCSC), an on-line tool, to provide a benefit-risk assessment for patients considering radical cystectomy.

Disclaimer:

License and Disclaimer: The software which is provided is freeware for personal use only. It is not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: https://www.utmb.edu/surgery/divisions-sections/urology/radical-cystectomy-survival-calculator/radical-cystectomy-survival-calculator. The author has made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publication. Results estimated with this software may be higher than those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus any decisions concerning patient care should not be based only on the use of this software, but should also take into account the patient's past history and other current patient and tumor characteristics. As medical science is constantly changing and human error is always possible, the author and UTMB do not warrant the software's accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of this software. In no event shall either the author or UTMB be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage. The author and UTMB specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of survival for patient with bladder cancer.The software provided hereunder is on an as is basis and neither the author nor UTMB have any obligations to provide maintenance, support, updates, enhancements or modifications.