Maruyama Lab Publications

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Research Articles

  1. Kimura, M, Matsuoka R, Taniguchi S, Maruyama J, Paessler S, Oka S, Yamashita A, Fukuhara T, Matsuura Y, Tani H. Inhibitors of cannabinoid receptor 1 suppress the cellular entry of Lujo virus. 2023. Virology. 109867.
  2. Manning JT, Maruyama J, Wanninger T, Reyna RA, Stevenson HL, Peng B, Mantlo EK, Huang C, Paessler S. The roles of XJ13 and XJ44-specific mutations within the Candid# 1 GPC in Junin virus attenuation. 2023. Front Immunol. 14:2884.
  3. Reyna RA, Maruyama J, Mantlo EK, Manning JT, Taniguchi S, Makishima T, Lukashevich IS, Paessler S. 2022. Depletion of CD4 and CD8 T cells reduces acute disease and is not associated with hearing loss in ML29-infected STAT1-/- mice. Biomedicines. 10(10):2433.
  4. Cao X, Maruyama J, Zhou H, Fu Y, Kerwin L, Powers C, Sattler RA, Manning JT, Singh A, Lim R, Healy LD, Johnson S, Cabral EP, Li D, Lu L, Ledesma A, Lee D, Richards S, Rivero Nava L, Li Y, Shen W, Stegman K, Blair B, Urata S, Kishimoto Urata M, Ko J, Du N, Morais K, Lawrence K, Rivera I, Pai CI, Bresson D , Brunswick M, Zhang Y, Ji H, Paessler S, Allen RD. 2022. Unbiased approach to identify and assess efcacy of human SARS‑CoV‑2 neutralizing antibodies. Sci Rep. 12:15517.
  5. Toba S, Sato A , Kawai M, Taoda Y, Unoh Y, Kusakabe S, Nobori H, Uehara S, Uemura K, Taniguchi K, Kobayashi M, Noshi T, Yoshida R, Naito A, Shishido T, Maruyama J, Paessler S, Carr MJ, Hall WW, Yoshimatsu K, Arikawa J, Matsuno K, Sakoda Y, Sasaki M, Orba Y, Sawa H, Kida H. Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses. 2022. Proc Natl Acad Sci USA. 119(36):e2206104119.
  6. Maruyama J, Reyna RA, Kishimoto-Urata M, Urata S, Manning JT, Harsell N, Cook R, Huang C, Nikolich-Zugich J, Makishima T, Paessler S. 2022. CD4 T-cell depletion prevents Lassa fever associated hearing loss in the mouse model. PLoS Pathog. 18(5):e1010557.
  7. Kishimoto-Urata M, Urata S, Kagoya R, Imamura F, Nagayama S, Reyna RA, Maruyama J, Yamasoba T, Kondo K, Hasegawa-Ishii S, Paessler S. 2022. Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit. Sci Rep. 12:5278.
  8. Mantlo E, Maruyama J, Manning JT, Wanninger TG, Huang C, Smith JN, Patterson M, Slobodan Paessler S, Koma T. 2022. Machupo Virus with Mutations in the Transmembrane Domain and Glycosylation Sites of the Glycoprotein Is Attenuated and Immunogenic in Animal Models of Bolivian Hemorrhagic Fever. J Virol. In press. DOI:10.1128/jvi.00209-22.
  9. Reyna RA, Kishimoto-Urata M, Urata S, Makishima T, Paessler S*, Maruyama J*. 2022. Recovery of anosmia in hamsters infected with SARS-CoV-2 is correlated with repair of the olfactory epithelium. Sci Rep. 12:628. *contributed equally
  10. Blake S, Shaabani N, Eubanks LM, Maruyama J, Manning JT, Beutler N, Paessler S, Ji H, Teijaro JR, Janda KD. 2021. Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model. ACS Infect Dis. 7(8):2229–2237.
  11. Koma T, Huang C, Coscia A, Hallam S, Manning JT, Maruyama J, Walker AG, Miller M, Smith JN, Patterson N, Abraham J, Paessler S. 2021. Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity. PLoS Pathog. 17(3):e1009356.
  12. Urata S*, Maruyama J*, Kishimoto-Urata M, Sattler RA, Cook R, Lin N, Yamasoba T, Makishima T, Paessler S. 2021. Regeneration profiles of olfactory epithelium after SARS-CoV-2 infection in golden Syrian hamsters. ACS Chem. Neurosci. 12(4):589-595. *contributed equally
  13. Suzuki T, Maruyama J, Cook R, Urata S, Paessler S, Makishima T. 2021. Auditory function analysis in immunodeficient STAT1 knock-out mice: considerations for viral infection models. Neuroscience Letters. 740:135427.
  14. Takadate Y, Manzoor R, Saito T, Kida Y, Maruyama J, Kondoh T, Miyamoto H, Ogawa H, Kajihara M, Igarashi M, Takada A. 2020. Receptor-Mediated Host Cell Preference of a Bat-Derived Filovirus, Lloviu Virus. Microorganisms. 8(10):1530.
  15. Hallam SJ, Manning JT, Maruyama J, Seregin A, Huang C, Walker DH, de la Torre JC, Paessler S. 2020. A single mutation (V64G) within the RING Domain of Z attenuates Junin virus. PLoS Negl Trop Dis. 14(9):e0008555.
  16. Furuyama W, Nanbo A, Maruyama J, Marzi A, Takada A. 2020 A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection. PLOS Negl Trop Dis. 14(9):e0008602.
  17. Saito T, Maruyama J, Nagata N, Isono M, Okuya K, Takadate Y, Kida Y, Miyamoto H, Mori-Kajihara A, Hattori T, Furuyama W, Ogawa S, Iida S, Takada A. 2020. A Surrogate Animal Model for Screening of Ebola and Marburg Glycoprotein-Targeting Drugs Using Pseudotyped Vesicular Stomatitis Viruses. Viruses. 12:9 923.
  18. Ulaankhuu A, Bazarragchaa E, Okamatsu M, Hiono T, Bodisaikhan K, Amartuvshin T, Tserenjav J, Urangoo T, Buyantogtokh K, Matsuno K, Hattori T, Kondoh T, Sato M, Takadate Y, Torii S, Isono M, Okuya K, Saito T, Kasajima N, Kida Y, Maruyama J, Igarashi M, Takada A, Kida H, Batchuluun D, Sakoda Y. 2020. Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019. Virus Genes. 56:472–479.
  19. Mantlo E, Bukreyeva N, Maruyama J, Paessler S, Huang C. 2020. Antiviral activities of type I interferons to SARS-CoV-2 infection. Antiviral Res. 179:104811.
  20. Mateer EJ, Maruyama J, Card G, Paessler S, Huang C. 2020. Lassa virus but not highly pathogenic New World arenaviruses restrict immunostimulatory dsRNA accumulation during infection. J Virol. 94:9
  21. Takadate Y, Kondoh T, Igarashi M, Maruyama J, Manzoor R, Ogawa H, Kajihara M, Furuyama W, Sato M, Miyamoto H, Yoshida R, Hill TE, Freiberg AN, Feldmann H, Marzi A, Takada A. 2019. Niemann-Pick C1 heterogeneity of bat cells controls filovirus tropism. Cell Rep. 30(2):308-319.
  22. Maruyama J, Mateer EJ, Manning JT, Sattler R, Seregin AV, Bukreyeva N, Jones FR, Balint JP, Gabitzsch ES, Huang C, Paessler S. 2019. Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs. Vaccine. 37(45): 6824-6831
  23. Maruyama J, Manning JT, Mateer EJ, Sattler R, Bukreyeva N, Huang C, Paessler S. 2019. Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation. mSphere. 4(5): e00428-19
  24. Kobayashi T, Matsugo H, Maruyama J, Kamiki H, Takada A, Maeda K, Takenaka-Uema A, Tohya Y, Murakami S, Horimoto T. 2019. Characterization of a novel species of adenovirus from Japanese microbat and role of CXADR as its entry factor. Sci Rep 9:573.
  25. Sato M, Maruyama J, Kondoh T, Nao N, Miyamoto H, Takadate Y, Furuyama W, Kajihara M, Ogawa H, Manzoor R, others. 2019. Generation of bat-derived influenza viruses and their reassortants. Sci Rep 9:1158.
  26. Nanbo A, Maruyama J, Imai M, Ujie M, Fujioka Y, Nishide S, Takada A, Ohba Y, Kawaoka Y. 2018. Ebola virus requires a host scramblase for externalization of phosphatidylserine on the surface of viral particles. PLoS Pathog 14:e1006848.
  27. Kondoh T, Letko M, Munster VJ, Manzoor R, Maruyama J, Furuyama W, Miyamoto H, Shigeno A, Fujikura D, Takadate Y, others. 2018. Single-nucleotide polymorphisms in human NPC1 influence filovirus entry into cells. J Infect Dis 218:S397-S402.
  28. Nguyen LT, Nakaishi K, Motojima K, Ohkawara A, Minato E, Maruyama J, Hiono T, Matsuno K, Okamatsu M, Kimura T, Takada A, Kida H, Sakoda Y. 2017. Rapid and broad detection of H5 hemagglutinin by an immunochromatographic kit using novel monoclonal antibody against highly pathogenic avian influenza virus belonging to the genetic clade 2.3.4.4. PLoS One 12:e0182228.
  29. Kondoh T, Manzoor R, Nao N, Maruyama J, Furuyama W, Miyamoto H, Shigeno A, Kuroda M, Matsuno K, Fujikura D, Kajihara M, Yoshida R, Igarashi M, Takada A. 2017. Putative endogenous filovirus VP35-like protein potentially functions as an IFN antagonist but not a polymerase cofactor. PLoS One 12:e0186450.
  30. Nakao R, Matsuno K, Qiu Y, Maruyama J, Eguchi N, Nao N, Kajihara M, Yoshii K, Sawa H, Takada A, others. 2017. Putative RNA viral sequences detected in an Ixodes scapularis-derived cell line. Ticks Tick Borne Dis 8:103–111.
  31. Maruyama J, Nao N, Miyamoto H, Maeda K, Ogawa H, Yoshida R, Igarashi M, Takada A. 2016. Characterization of the glycoproteins of bat-derived influenza viruses. Virology 488:43–50.
  32. Furuyama W, Marzi A, Nanbo A, Haddock E, Maruyama J, Miyamoto H, Igarashi M, Yoshida R, Noyori O, Feldmann H, others. 2016. Discovery of an antibody for pan-ebolavirus therapy. Sci Rep 6:20514.
  33. Furuyama W, Marzi A, Carmody AB, Maruyama J, Kuroda M, Miyamoto H, Nanbo A, Manzoor R, Yoshida R, Igarashi M, others. 2016. FcγII-receptor iia-mediated src signaling pathway is essential for the antibody-dependent enhancement of ebola virus infection. PLoS Pathog 12:e1006139.
  34. Ogawa H, Miyamoto H, Nakayama E, Yoshida R, Nakamura I, Sawa H, Ishii A, Thomas Y, Nakagawa E, Matsuno K, others. 2015. Seroepidemiological prevalence of multiple species of filoviruses in fruit bats (Eidolon helvum) migrating in Africa. J Infect Dis 212:S101--S108.
  35. Kuroda M, Fujikura D, Nanbo A, Marzi A, Noyori O, Kajihara M, Maruyama J, Matsuno K, Miyamoto H, Yoshida R, others. 2015. Interaction between TIM-1 and NPC1 is important for cellular entry of Ebola virus. J Virol 89:6481–6493.
  36. Hiono T, Ohkawara A, Ogasawara K, Okamatsu M, Tamura T, Chu D-H, Suzuki M, Kuribayashi S, Shichinohe S, Takada A, Ogawa H, Yoshida R, Miyamoto M, Nao N, Furuyama W, Maruyama J, Eguchi N, Ulziibat G, Enkhbold B, Shatar M, Jargalsaikhan T, Byambadorj S, Damdinjav B, Sakoda Y, Kida H. 2015. Genetic and antigenic characterization of H5 and H7 influenza viruses isolated from migratory water birds in Hokkaido, Japan and Mongolia from 2010 to 2014. Virus Genes 51:57–68.
  37. Nao N, Kajihara M, Manzoor R, Maruyama J, Yoshida R, Muramatsu M, Miyamoto H, Igarashi M, Eguchi N, Sato M, others. 2015. A single amino acid in the M1 protein responsible for the different pathogenic potentials of H5N1 highly pathogenic avian influenza virus strains. PLoS One 10:e0137989.
  38. Maruyama J, Miyamoto H, Kajihara M, Ogawa H, Maeda K, Sakoda Y, Yoshida R, Takada A. 2014. Characterization of the envelope glycoprotein of a novel filovirus, lloviu virus. J Virol 88:99–109.
  39. Muramatsu M, Yoshida R, Yokoyama A, Miyamoto H, Kajihara M, Maruyama J, Nao N, Manzoor R, Takada A. 2014. Comparison of antiviral activity between IgA and IgG specific to influenza virus hemagglutinin: increased potential of IgA for heterosubtypic immunity. PLoS One 9:e85582.
  40. Yamaguchi H, Kobayashi S, Maruyama J, Sasaki M, Takada A, Kimura T, Sawa H, Orba Y. 2014. Role of the C-terminal region of vervet monkey polyomavirus 1 VP1 in virion formation. J Vet Med Sci 13–568.
  41. Kuroda M, Fujikura D, Noyori O, Kajihara M, Maruyama J, Miyamoto H, Yoshida R, Takada A. 2014. A polymorphism of the TIM-1 IgV domain: Implications for the susceptibility to filovirus infection. Biochem Biophys Res Commun 455:223–228.
  42. Muramatsu M, Yoshida R, Miyamoto H, Tomabechi D, Kajihara M, Maruyama J, Kimura T, Manzoor R, Ito K, Takada A. 2013. Heterosubtypic antiviral activity of hemagglutinin-specific antibodies induced by intranasal immunization with inactivated influenza viruses in mice. PLoS One 8:e71534.
  43. Noyori O, Nakayama E, Maruyama J, Yoshida R, Takada A. 2013. Suppression of Fas-mediated apoptosis via steric shielding by filovirus glycoproteins. Biochem Biophys Res Commun 441:994–998.
  44. Maruyama J, Okamatsu M, Soda K, Sakoda Y, Kida H. 2013. Factors responsible for pathogenicity in chickens of a low-pathogenic H7N7 avian influenza virus isolated from a feral duck. Arch Virol 158:2473–2478.
  45. Hattori T, Arikawa T, Fujioka Y, Maruyama J, Nakayama Y, Ohba Y, Niki T, Miyazaki T, Hirashima M, Kida H. 2013. Inhibition of influenza A virus infection by Galectin-9. Jpn J Vet Res 61:5–18.

 

Review Articles

  1. Saito T, Reyna RA, Taniguchi S, Littlefield K, Paessler S, Maruyama J. 2023. Vaccine candidates against arenavirus infections. Vaccines. 11(3):635.
  2. Wanninger TG, Millian DE, Saldarriaga OA, Maruyama J, Saito T, Reyna RA, Taniguchi S, Arroyave E, Stevenson HL, Paessler S. 2022. Macrophage infection, activation, and histopathological findings in ebolavirus infection. Front Cell Infect Microbiol. 12:1485.
  1. 2.    Hallam S, Koma T, Maruyama J, Paessler S. 2018. Review of Mammarenavirus biology and replication. Front Microbiol 9:1751.
  2. 3.    Sattler RA, Maruyama J, Shehu NY, Makishima T, Paessler S. 2019. Current small animal models for LASV hearing loss. Curr Opin Virol. 37:118-122.