My laboratory research has mainly focused on vaccine development and understanding of the disease mechanisms of emerging and re-emerging RNA viruses, such as West Nile virus, Zika virus, Powassan virus, Chikungunya virus, and Sars-COV-2.

BS	Anhui University, P.R.China	Microbiology	1992
PhD	University of Texas Medical Branch, Galveston	Immunology	2000
Post-Doctoral	Yale University, School of Medicine	Infectious Disease	2004

1997-2000	James W. McLaughlin Predoctoral Fellowship, UTMB
1999	Christina Fleischmann Scholarship Award, UTMB
2001, 2003	Kempner Postdoctoral Fellowship, UTMB
2002-2003	Postdoctoral Fellowship in Rheumatology, Yale University
2005, 2006	AAI Junior Faculty Travel Award
2013, 2018	AAI Laboratory Travel Grant
2018-2022	Member, Virology B Study Section, NIH

Membership in professional societies

• 1999- Present: Trainee & Regular Member, American Association of Immunologist
• 2003- Present: Associate & Regular Member, American Society for Virology
• 2006- Present: Member, American Association for the Advancement of Science
• 2009- Present: Member, Center for Biodefense and Emerging Infectious Disease, UTMB
• 2010- Present: Member, Sealy Center for Vaccine Development, UTMB
• 2015- Present: Faculty of 1000 (F1000)

Service/Outreach

• 2005- Present: Ad hoc reviewer for 46 Scientific Journals, including Sci Transl Med., PLoS Pathog, J Immunol, Emerg Infect Dis, PLoS Negl Trop Dis, J Infect Dis, Viruses, J Virol. etc.
• 2006: VA Grant External Reviewer
• 2007- Present: Ad hoc reviewer, NIH study section special emphasis panels participated: “Immune Mechanisms of Viral Control”; “Cooperative Centers for Translational Research on Human Immunology and Biodefense (U19)”; ZRG1 IMM-K 02 M; “Rapid assessment of Zika virus complications (R21)"; ZRG1 IMM-U90 “Immune responses to pathogens and/or vaccine development”; ZRG1 IMM AREA U81; IMM Fellowship F07-U20; ZRG1 IDM-P (90)S Zika virus Complications; ZRG1 IDM-U (07) S Zika virus Complications. NIH standing study sections participated: Virology B; NIAID HIPC; F13 Fellowship Infectious Diseases and Microbiology; Clinical Neuroimmunology and BrainTumors; ZES1 RAM-K (LP) 1 Extramural Loan Repayment Program for Clinical Researchers
• 2011- Present: Academic Editor, PLoS One
• 2012: Grant reviewer, Austrian Science Fund
• 2013: Grant reviewer, Einstein Foundation Berlin
• 2015- Present: Reviewer Editor, Frontiers in Microbial Immunology, Frontiers in Cellular and Infection Microbiology, and Frontiers in Virology
• 2016: External grant reviewer, Natural Sciences and Engineering Research Council, Canada
• 2017: Grant reviewer, Medical Research Council, United Kingdom
• 2019- Present: Associate Editor, Virology Journal
• 2019: Guest Editor, Viral Immunology, Pathogens
• 2019: Co-Director, NIAID Infectious Diseases and Inflammation training program, UTMB

1. Saxena V, Xie G, Li B, Farris T, Welte T, Gong B, Boor P, Wu P, Tang SJ, Tesh R, and Wang T. (2013). A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice. PLoS Negl Trop Dis. 7(6):e2275.
2. Wang T and Welte T. (2013). Natural killer and Gamma/delta T cells Control of West Nile virus infection. Viruses 2013, 5, 2298-2310.
3. Xie G, Welte T, Wang J, Whiteman MC, Wicker JA, Saxena V, Cong Y, Barrett AD, and Wang T. (2013). A West Nile Virus NS4B P38G mutant strain induces adaptive immunity via TLR7-MyD88- dependent and independent signaling pathways. Vaccine. 31(38):4143-51.
4. Xie G, Luo H, Pang L, Peng BH, Winkelmann E, McGruder M, Hesse J, Whiteman M, Campbell G, Milligan G, Cong Y, Barrett AD, and Wang T. (2015). Dysregulation of TLR7 impairs innate and adaptive T cell responses and host resistance to an attenuated West Nile Virus infection in old mice. J Virol. 90(3):1333-44.
5. Winkelmann ER, Luo H and Wang T. (2016). West Nile Virus Infection in the Central Nervous System [version 1; referees: 3 approved]. F1000Research. 2016, 5(F1000 Faculty Rev):105.
6. Erasmus JH, Auguste AJ, Kaelber JT, Luo H, Rossi SL, Fenton K, Leal G, Dal Kim D, Chiu W, Wang T, Frolov I, Nasar F, Weaver SC. 2016. A Chikungunya Fever Vaccine Utilizing an Insect Specific Virus Platform. Nat Med. 23(2):192-199.
7. Luo H, Winkelmann E, Xie G, Fang R, Peng BH, Li L, Lazear H, Paessler S, Diamond MS, Gale M, Barrett AD, and Wang T. 2017. MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection. J Virol. 91(6). pii: e02097-16.
8. Saxena V, Bolling B, and Wang T. 2017. West Nile Virus. Clin Lab Med. 37(2):243-252.
9. Shan C, Murato A, Nunes BTD, Luo H, Xie X, Medeiros BA, Tesh RB, Barrett AD, Vascincelos, Wang T, Weaver SC, Rossi SL, Shi PY. A live attenuated Zika virus vaccine with a 3' UTR deletion. Nat Med. 23(6):763-767.PMID:28394328.
10. Zhu S, Luo H, Liu H Ha Y, Mays ER, Lawrence RE, Winkelmann E, Smith SB, Wang M, Wang T, & Zhang W. p38MAPK plays a critical role in induction of a proinflammatory phenotype in retinal Müller cells following Zika virus infection. Antiviral Res.145:70-81.
11. Fontes CR, Shan C, Luo H, Muruato AE, Medeiros D, Mays ER, X Xie, J Zou, CM Roundy, M Wakamiya, SL Rossi, Wang T, SC Weaver, PY Shi. 2017. Functional analysis of glycosylation of Zika virus envelope protein. Cell Reports 21, 1180–1190.
12. Xia H, H Luo, C Shan, AE Muruato, BTD Nunes, DBA Medeiros, X Xie, PFC Vasconcelos, SC Weaver, Wang T, R Rajsbaum, PY Shi. 2018. An evolutionary mutation enhances Zika virus evasion of host interferon induction. Nat Commun. 9(1):414. doi: 10.1038/s41467-017-02816-2.PMID:29379028
13. Luo H, ER Winkelmann, I Fernandez-Salas, L Li, S Mayer, R Danis-Lozano, RM Sanchez-Casas, N Vasilakis, R Tesh, AD Barrett, SC Weaver, and Wang T. 2018. Zika, dengue and yellow fever viruses induce differential anti-viral immune responses in human monocytic and first trimester trophoblast cells. Antiviral Res. pii: S0166-3542(17)30707-6. doi: 10.1016/j.antiviral.2018.01.003.
14. Luo H and Wang T. Recent advances in understanding West Nile virus host immunity and viral pathogenesis. F1000Res. 2018 Mar 19;7:338. doi: 10.12688/ f1000research.13362.1. eCollection 2018. Review.
15. Li G. Teleki C and Wang T. Memory T cells in Flavivirus vaccination. (Review). Vaccines (Basel). 2018 Oct 18;6(4). pii: E73. doi: 10.3390/vaccines6040073.
16. Luo H, Winkelmann ER, S Zhu, W Ru, E Mays, JA Silvas, LL Vollmer, J Gao, BH Peng, NE Bopp, C Cromer, C Shan, G Xie, G Li, R Tesh, VL Popov, PY Shi, SC Sun, P Wu, RS Klein, SJ Tang, W Zhang, PV. Aguilar, and Wang T. 2018. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018 Nov 1;128(11):4980-4991. doi: 10.1172/JCI99902. Epub 2018 Sep 24.
17. X Xie, DB. Kum, H Xia, H Luo, C Shan, J Zou, AE Muruato, DBA Medeiros, BTD Nunes, K Dallmeier, SL Rossi, SC Weaver, J Neyts, Wang T, PFC Vasconcelos, PY Shi. A single-dose live-attenuated Zika virus vaccine with controlled infection rounds. 2018. Cell Host Microbe. 2018 Oct 10;24(4):487-499.e5. doi: 10.1016/j.chom.2018.09.008
18. Li G, Awad A, Luo H, C Shan, Cao Z, Camila R. Fontes-Garfias2V Sarathy, C Teleki, E Winkelmann, Y Liang, J Sun, N Bourne, AD Barrett, PY Shi, and Wang T. 2019. An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses. NPJ Vaccines. 2019 Nov 28;4:48. doi: 10.1038/s41541-019-0143-3. eCollection 2019. PMID:31815005
19. Webb EM, Sasha A, Haller S, Langsjoen RM, Luo H, Plante K, Wang T, Weaver SC, Rossi SL, Auguste AJ. Effects of Chikungunya immunity on Mayaro virus disease and epidemic potential in the New World. Sci Rep. 2019 Dec 31;9(1):20399. doi: 10.1038/s41598-019-56551-3. PMID:31892710
20. Luo H, G Li, B Wang, B Tian, J Gao, Zou J, S Shi, Zhu S, BH Peng, Adam A, A Martinez, K Hein, ER Winkelman, Y Mahmoud, Zhou X, C Shan, S Rossi, S Weaver, ADT Barrett, SC Sun, W Zhang, PY Shi, P Wu, and Wang T. Peli1 signaling blockade attenuates congenital zika syndrome. PLoS Pathog. 2020 Jun 16;16(6):e1008538. doi: 10.1371/journal.ppat.1008538. eCollection 2020 Jun.PLoS Pathog. 2020. PMID: 32544190

Complete list of published works in My Bibliography https://www.ncbi.nlm.nih.gov/myncbi/tian.wang.1/bibliography/public/