Bin Gong, MD, PhD

I have more than 11 years of research experience involving experimental tomographic-pathologic studies of microvascular diseases with emphasis on mechanisms of integrity of endothelial junctions and extracellular matrices, as well as past research experience with cardiovascular diseases. My research focus is to develop post-transcriptional or translational regulation strategies to protect endothelial cells during infection with intracellular pathogens, most notably Rickettsia spp.

MD	Second Military Medical University, Shanghai, China	Medicine	1990
PhD	Second Military Medical University, Shanghai, China	Experimental Cardiothoracic Research Science	1996
Postdoctoral	University of Texas Medical Branch, Galveston, TX	Experimental Pathology	2007

2006	Travel Award (“Imaging of Extracellular Matrix in Chemical-induced Developmental Dissecting Aortic Aneurysm using Multiphoton Fluorescence and Second Harmonic Generation Microscopy: Defective Collagen Type 3”). Weinstein Cardiovascular Development Conference St. Petersburg, Fl
2005	First Place Postdoctoral Fellow Award (“Morphogenic Study on Dissecting Aortic Aneurysm with Multiphoton and Second Harmonic Generation Microscopy”). Department of Pathology, University of Texas Medical Branch-Galveston, TX
2005	Third Place Society of Toxicology Trainee Award 2005 (“Fetal Basis of Dissecting Aortic Aneurysm”). National Institute of Environmental Health Sciences
2005	Outstanding Achievement Award (“Morphologic Study of Extracellular Matrix in Chemical-induced Developmental Dissecting Aortic Aneurysm Using Multiphoton Florescence and Second Harmonic Generation Microscopy”). 2005 Society of Toxicology Meeting, New Orleans, LA
2005	Second Place Postdoctoral Fellow Award (“Efficient Transgene Expression of Glutathione-s-transferases [GST] in Cardiovascular Cells and Tissues Mediated by Adenoviral Vectors”). Department of Pathology, University of Texas Medical Branch-Galveston, TX
2004	First Place Postdoctoral Fellow Award (“A Developmental Dissecting Aortic Aneurysm Model”). Department of Pathology, University of Texas Medical Branch-Galveston, TX
2004	Best Poster Award (“Cardiac Preconditioning with Infrared Laser Irradiation Heating”). International Education Week Scientific Poster, University of Texas Medical Branch-Galveston, TX

2008-Present	The United States & Canadian Academy of Pathology (USCAP)
2008-Present	American Society for Clinical Pathology (ASCP)
2004-Present	North American Vascular Biology Organization (NAVBO)

Bin Gong, Jun Fey, Chili Zhang. Applied anatomy of Inferior Vena Cava in human. Anatomy 1990; 13(1): 43
Rukun Chen; Wei Lu, Bin Gong, et al. Experimental study Effect of necrosis of cardiac papillary muscle on mitral valve function. Shanghai Biomedical Engineering Science 1992; 4(39): 2.
Bin Gong, Chapter 8: Organic Transplantation. In Youhua Zhu edited Handbook of Urology: diagnosis and treatment, The first edition, National Health and Medicine Publish Company, Beijing, 1992.
Bin Gong, Dehong Yu. Modern Bioengineering Therapy with Laser in Anal rectal Disease. National Journal of Anal rectal Disease 1994; 14(5): 25.
Bin Gong, Baoren Zhang, Jialing Zhu, et al. Perioperative change of plasma Endothelin-1 in patients undergoing heart valve replacement. Acad. J. Sec. Mil. Med. Univer. 1997; 18(supl): 55-58.
Bin Gong, Jialing Zhu, Baoren Zhang, et al. Experimental study on transplantation and reanimation of asphyxiated cadaver non-beating heart in rat. Acad. J. Sec. Mil. Med. Univ. 1999; 20(12): 1043-1044.
Heling Zhang, Yan Men, Bin Gong. Integrate therapeutic method for general thoracic cancer. Acad. J. Sec. Mil. Med. Univer. 2000; 21(8): 1166.
Yang LQ, Yu WF, Cao YF, Gong B, Chang Q, Yang GS. Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes. World J Gastroenterol. 2003 Sep;9(9):1959-62.
Bin Gong, Andres Oberhauser, Paul Boor. A development model of dissecting aortic aneurysm. Endothelium 2003;10(6)371.
Bin Gong, Paul Boor: The role of amine oxidases in xenobiotic metabolism. Expert Opin Drug Metab Toxicol. 2006 Aug;2(4):559-71. Review.
Bin Gong, Paul J. Boor, et al: Chemical induced, nonlethal, developmental model of dissecting aortic aneurysm. Birth Defects Research Part A: Clinical and Molecular Teratology 2006;76:29-38.
Paul Boor, Yonzhen Yang, and Bin Gong: Role of the Media in Vascular Injury: Atherosclerosis and Dissection. Toxicologic Pathology 34:33-38, 2006
Bin Gong; Thomas Albrecht; Paul Boor; et al: Whole-body hyperthermia induces up-regulation of vascular endothelial growth factor accompanied by neovascularization in cardiac tissue. Life Sciences 2006 Oct 4;79(19):1781-8.
Xu Y, Gong B, Boor P, et al. Glutathione-S-Transferase Protects against Oxidative Injury of Endothelial Cell Tight Junctions. Endothelium. 2007 Nov-Dec;14(6):333-43.
Bin Gong, Ju Sun, et al: Nonlinear Imaging Study of Extracellular Matrix in Chemical-induced, Developmental Dissecting Aortic Aneurysm: Evidence for Defective Collagen Type III. Birth Defects Research Part A: Clinical and Molecular Teratology 2008 Jan;82(1):16-24.
Gong B, Boor PJ, Motamedi M, et al. Cardiac preconditioning with local laser-induced hyperthermia. J. Surg Res. 2008 Oct;149(2):177-83.
Ya Xu, Bin Gong, et al. Adenovirus-Mediated Overexpression of Glutathione-STransferase Mitigates Transplant Arteriosclerosis in Rabbit Carotid Allografts. Transplantation 2010 Feb 27;89(4):409-16.

NIH Biosketch

Bin Gong, MD, PhDAssociate Professor

Bin Gong, MD, PhD
Associate Professor