• I have had a long interest on laboratory test utilization, particularly as it relates to coagulation studies, my area of expertise. A principal focus of the work has been the identification of diagnostic errors and mechanisms to prevent them.
• I have been a fatty acid biochemist for 35 years. My early research career included the study of biological mechanisms associated with the conversion of fatty acids into eicosanoids. The focus was to identify the pool of eicosanoid precursor fatty acids in the cell and how they became available for eicosanoid production. I later investigated the covalent association of fatty acids to proteins by thioester linkages with Dr. Laszio Muszek, who was later elected to the Hungarian National Academy of Sciences. My laboratory also included fatty acid related studies involved an esterification product of ethanol and fatty acids, fatty acid ethyl esters (FAEE), and fatty acid abnormalities found in patients with cystic fibrosis.
• I have continuously written articles on topics related to diagnosis of coagulation disorders and optimization of clinical laboratory operations. This led to the production of several books, including a major textbook entitled Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory, published by McGraw-Hill in the prestigious Lange series of medical textbooks. The third edition has been named Laposata’s Laboratory Medicine.

> 200 publications