Maternal-Fetal Pharmacology and Bio-Drug Development Research
Director: Mahmoud Ahmed PhD
The Department of Obstetrics & Gynecology has a long history of encouraging physician-scientists to participate in clinical studies to continually improve the health outcomes for women and their infants at UTMB and across the word. Many of our clinicians participate in studies funded by governmental, industry, and private agencies, with an eye to determining risk factors during pregnancy, as well as establishing safe evidence-based treatments for women during pregnancy.
Our research focuses on pharmacologic outcomes in pregnant women. The study of drugs used during pregnancy is one of the most neglected areas in clinical pharmacology and drug research. The lack of Food and Drug Administration obstetric labeling and the universal off-label use of drugs in pregnancy are the direct result of the inadequacy of research and clinical trials of drugs in this special population. A major goal of this program is to identify, characterize, and study those drugs that are of therapeutic value during pregnancy and whose clinical pharmacology (both pharmacokinetics and pharmacodynamics) is altered by the pregnant state in normal or abnormal pregnancies. We also serves as a UTMB resource for training health professionals in obstetric-fetal pharmacology and drug trials in pregnant women.