Pot Damages the teen Brain

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Cannabinoid Exposure During Adolescence Disrupts Neural Regulation
Young rats injected with a synthetic cannabinoid have more of the brain's motivating dopaminergic signaling and fewer numbers of inhibitory neurons than controls...

National Institute on Drug Abuse for Teens Marijuana Fact Page
Marijuana is the dried leaves and flowers of the Cannabis sativa or Cannabis indica plant. Stronger forms of the drug include high potency strains - known as sinsemilla (sin-seh-me-yah), hashish (hash for short), and extracts including hash oil, shatter, wax, and budder. Of the more than 500 chemicals in marijuana, delta-9-tetrahydrocannabinol, known as THC, is responsible for many of the drug's psychotropic (mind-altering) effects. It's this chemical that distorts how the mind perceives the world. In other words, it is what makes you high...

602.07 / HHH1 - Adolescent cannabinoid exposure increases nigrostriatal dopaminergic transmission
Adolescence is a period characterized by gradual behavioral and physiological transition from childhood to adulthood. During adolescence, critical neuronal circuits changes to respond to physiological changes and to adapt to environmental stimuli (Sturman and Moghaddam 2011). In particular, nigrostriatal dopaminergic (DA) pathways are in constant change during the development of animals (McCutcheon and Marinelli 2009). In early adolescence, the DA activity is lower compared to adulthood, but during the middle and late adolescence, the DA activity is higher than in adults (McCutcheon and Marinelli 2009; Naneix et al 2012). The dynamic changes observed in DA circuits suggest that adolescence is a period of high vulnerability to the long-term effects associated to drugs of abuse (Schneider 2008)...