| Dilute Russell Viper Venom Test (089-0526) | |
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| Test Mnemonic: | DRVVT
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| Specimen Requirements: | |
| Collection: | Blue-topped (3.2% sodium-citrate) tube. Routine venipuncture; discard 1st mL of blood by collecting a discard tube prior to collecting the blue-topped (3.2% sodium-citrate) tube. For collections with butterfly blood collection sets, a discard tube should also be collected prior to collection of the blue top to ensure sufficient sample volume. Drawing a discard tube will displace the air from the blood collection set tubing to ensure proper blood draw volume. Volume: 2.7 mL or 1.8 mL blood, ( blue top tube must be full)
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| Container: | Blue-topped (3.2% sodium-citrate) tube |
| Storage/Transport: | Whole blood is viable for 4 hours at room temperature. If time from draw to receipt in the laboratory is to be greater than 4 hours, centrifuge the specimen for 15 minutes at 1500g and separate the plasma from the cells. · Transfer plasma to 12x75 plastic tube
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| Stability: | Whole blood 4 hours at room temperature, Plasma 4 hrs at 2-4°C. Frozen plasma 2 weeks stored at -20°C.
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| Causes for Rejection: | QNS, clotted, severely hemolyzed, specimen greater than 4 hours old, wrong tube, sample identification error, sample processed/transported and/or stored improperly.
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| Reference Range: |
DRVVT Check: < 44.1 seconds = No significant evidence of Lupus Anticoagulant
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| Turnaround Time: | 7 days (call lab for schedule).
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| Methodology: | Screening test (DRVVT Check) is performed using the Electromechanical viscosity detection system. If result is >44.1 seconds, a second test is performed, this time with an excess of phospholipids to neutralize any remaining Lupus Anticoagulant (DRVVT Sure). The ratio Check /Sure is then calculated.
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| Performed: | Samples are accepted 24 hours per day at Sample Management, 7.412 CSW Bldg.
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| Clinical Indication: | Component of the Lupus Anticoagulant Panel. DRVVT Check screens for Lupus-like anticoagulants (antiphospholipid antibodies). DRVVT Check/Sure ratio is used to support the presence or absence of lupus anticoagulants in plasma. |
| CPT 4 Code: | 85613
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| Note: | If applicable, state clinical information that is required to be provided with specimen
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| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |