| Anti-Ribosomal P Antibody (8000100826) | |
|---|---|
| Test Mnemonic: | |
| Specimen Requirements: | |
| Collection: | Serum separator tube (SST) Red top serum tube with no additive |
| Container: | Serum separator tube (SST) Red top serum tube with no additive |
| Minimum Volume: | 1 mL of serum |
| Storage/Transport: | Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C) |
| Specimen Preparation: | Within 2 hours of collection, centrifuge. Serum collected in a red top tube should be removed from the red cells if testing will be delayed. |
| Stability: | Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C) |
| Causes for Rejection: | Improper collection, gross hemolysis. Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form |
| Reference Range: | Positive - Antibody detected. Negative - No antibody detected |
| Turnaround Time: | Test is performed in batch, once per day, six days a week. |
| Methodology: | Multiplexing bead immunoassay |
| Performed: | Clnical Microbiology |
| Synonyms: | RIBO P |
| Clinical Indication: | Autoimmune disease testing |
| CPT 4 Code: | 83516 |
| Note: | Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than fivefold during and before active phases of psychosis. |
| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |