| Anti-Chromatin Antibody (8000100936) | |
|---|---|
| Test Mnemonic: | |
| Specimen Requirements: | |
| Collection: | Serum separator tube (SST) Red top serum tube with no additive |
| Container: | Serum separator tube (SST) Red top serum tube with no additive |
| Minimum Volume: | 1mL of serum |
| Storage/Transport: | Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C) |
| Specimen Preparation: | Within 2 hours of collection, centrifuge. Serum collected in a red top tube should be removed from the cells if testing will be delayed. |
| Stability: | Refrigerate (2-8°C) up to 7 days; Samples should be frozen (<-20°C) |
| Causes for Rejection: | Improper collection, gross hemolysis. Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form. |
| Reference Range: | Positive - Antibody detected. Negative - No antibody detected |
| Turnaround Time: | Test is performed in batch, once per day, six days a week. |
| Methodology: | Multiplexing bead immunoassay |
| Performed: | Clinical Microbiology |
| Synonyms: | Chromatin Antibody; ENA Antibodies |
| Clinical Indication: | Autoimmune disease screening |
| Patient Preparation : | Routine venipuncture |
| CPT 4 Code: | 83516 |
| Note: | The presence of anti-chromatin antibodies may be useful in the diagnosis of systemic lupus erythematous (SLE) or drug-induced lupus (DIL) and have been reported to be predictive of lupus nephritis. |
| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |