| Epstein Barr Virus (EBV) Viral Capsid Antibody, IgM (8000100257) | |
|---|---|
| Test Mnemonic: | |
| Specimen Requirements: | |
| Collection: | SST (gold top) tube |
| Container: | SST |
| Minimum Volume: | 1 mL of serum |
| Storage/Transport: | Room temperature. Refrigerate 2-8'C if delay in transport |
| Specimen Preparation: | Within 2 hours of collection, centrifuge |
| Stability: | 7 days refrigerated; indefinitely frozen |
| Causes for Rejection: | Lipemic, hemolysis, bacterial contamination, improper collection. Specimen container unlabeled or labeled incorrectly. No date and time of collection or no collector information on order. |
| Reference Range: | Negative |
| Turnaround Time: | Test is performed daily, Monday through Friday |
| Methodology: | Multiplex Bead Immunoassay |
| Performed: | Clinical Microbiology |
| Synonyms: | Epstein Barr Virus Viral Capsid Antibody, IgM; EBV Viral Capsid Antibody, IgM; EBV IgM; EBV Viral Capsid IgM; EBVM |
| Clinical Indication: | Suspected infection with Epstein Barr virus. Detection of EBV VCA IgM antibody suggests acute infection. Order in conjuction with EBV IgG and EBNA antibodies to differentiate acute, recent, and past infection. |
| Patient Preparation : | Routine venipuncture |
| CPT 4 Code: | 86665 |
| Note: | IgM antibodies to VCA are normally present during acute EBV infection, and generally absent in convalescence. The presence of antibodies in otherwise healthy individuals usually indicates exposure either as silent primary infection or reactivation. Antibody levels tend to rise and peak after 3 - 4 weeks, then decline and usually dissipate after 2 - 3 months. Previously positive patients do not require repeat testing. If the patient has no detectable antibody, it is recommended to wait at least two weeks before testing again. If results are equivocal, a second sample should be collected and tested. |
| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |