| Anti-Sm (SMITH) Antibody (8000100305) | |
|---|---|
| Test Mnemonic: | |
| Specimen Requirements: | |
| Collection: | SST ( serum separator tube) - yellow top |
| Container: | SST |
| Minimum Volume: | 1 mL of serum |
| Storage/Transport: | Room temperature. Refrigerate 2-8'C if delay in transport |
| Specimen Preparation: | Within 2 hours of collection, centrifuge |
| Stability: | 7 days refrigerated; indefinitely frozen |
| Causes for Rejection: | Improper collection, gross hemolysis. Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form. |
| Reference Range: | Smith antibody is very specific for systemic lupus erythematosus (SLE) but only occurs in 30-35% of SLE cases. The presence of antibodies to Smith is often associated with renal disease. |
| Turnaround Time: | Test is performed daily, Monday through Friday |
| Methodology: | Multiplexing bead immunoassay |
| Performed: | Clinical Microbiology |
| Synonyms: | Smith Antibody; Sm Antibody; ENA Antibodies |
| Clinical Indication: | Autoimmune disease testing |
| CPT 4 Code: | 86235 |
| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |