Anti-Centromere B Antibody (8000100453) | |
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Test Mnemonic: | |
Specimen Requirements: | |
Collection: | SST ( serum separator tube) - yellow top |
Container: | SST |
Minimum Volume: | 1mL of serum |
Storage/Transport: | Room temperature. Refrigerate 2-8'C if delay in transport |
Specimen Preparation: | Within 2 hours of collection, centrifuge |
Stability: | 7 days refrigerated; indefinitely frozen |
Causes for Rejection: | Improper collection, gross hemolysis. Specimen container unlabeled or labeled incorrectly. No date and time of collection on requisition form. |
Reference Range: |
Centromere antibody is present in 80-90% of individuals with CREST variant scleroderma. This antibody is also seen in 30% of Raynaud patients, 12% of patients with mixed connective-tissue disease, diffuse scleroderma, interstitial pulmonary fibrosis, primary biliary cirrhosis, and in a smaller percent of patients with systemic lupus erythematosus (SLE) and RA.
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Turnaround Time: | Test is performed daily, Monday through Friday |
Methodology: | Multiplexing bead immunoassay |
Performed: | Clinical Microbiology |
Synonyms: | Centromere Antibody; ENA Antibodies; Anti-Centromere Antibody |
Clinical Indication: | Autoimmune disease screening
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Patient Preparation : | Routine venipuncture |
CPT 4 Code: | 83516 |
When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. |